Dra. Carolina Ortube – Directora Dpto. Investigación CIMO

Departamento de Investigación de Clínica Cimo

Directora: Dra. Carolina Ortube

Nacida en Argentina, ha ejercido como investigadora durante 7 años en Jules Stein Eye Institute, UCLA, especializándose en retina y genética. Su campo de acción abarca estrabismo, oftalmología infantil y neurooftalmología.

Como investigadora ha realizado diversas publicaciones en varias revistas científicas internacionales, las cuales se detallan a continuación:




  • Genetic ME-a visualization application for merging and editing pedigrees for genetic studies. BMC Res Notes. 16 Jun 2015.


  • Endophenotypes for Age-related Macular Degeneration: Extending our reach into the preclinical stages of disease. J Clin Med. 28 Nov 2014.


  • Whole exome sequencing detects homozygosity for ABCA4 p.Arg602Trp missense mutation in a pediatric patient with rapidly progressive retinal dystrophy. BMC Med Genet. 20 Ene 2014.


  • A novel web-based clinical research tool for a nationwide research study. J. Clin. Res. Bioethics 2013.


  • Seven new loci associated with age-related macular degeneration. Nat Genet. Abr 2013.


  • Comparative regional pupillography as a noninvasive biosensor screening method for diabetic retinopathy. Invest Ophthalmol Vis Sci. 2 Ene 2013.


  • Molecular diagnosis of putative Stargardt Disease probands by exome sequencing. BMC Med Genet. 3 Ago 2012.


  • Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype. Int J Epidemiol. 2012.


  • Sustained Elevated Intraocular Pressures after Intravitreal Injection of Bevacizumab, Ranibizumab, and Pegaptanib. Retina. Jun 2011.


  • Ocular manifestations of oblique facial clefts. J. Craniofac. Surg. Sep 2010.


  • Orbital ectopic brain tissue in Aicardi syndrome. J. Craniofac. Surg.Sep  2010.


  • High-resolution magnetic resonance imaging of the extraocular muscles and nerves demonstrates various etiologies of third nerve palsy. Am. J. Ophthalmol. Feb 2007.


  • Orbital magnetic resonance imaging of extraocular muscles in chronic progressive external ophthalmoplegia: specific diagnostic findings. J.AAPOS. Oct 2006.


  • High-resolution magnetic resonance imaging demonstrates abnormalities of motor nerves and extraocular muscles in patients with neuropathic strabismus. J.AAPOS. Abr 2006.


  • High-resolution magnetic resonance imaging demonstrates varied anatomic abnormalities in Brown syndrome. J. AAPOS. Oct 2005.


  • Orbital imaging demonstrates occult blowout fracture in complex strabismus. J. AAPOS. Jun 2004.

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